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Testosterone to estradiol ratio calculator

Convert common laboratory units before calculating a clearly defined hormone ratio, or solve for either concentration without assigning diagnostic cut-offs.

Calculator

Conventional mixed-unit T/E2 number
5.000
Testosterone (ng/dL)
500.000
Estradiol (pg/mL)
100.000
Testosterone in the selected input unit
500.000
Estradiol in the selected input unit
100.000

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How this calculator works

This page reports the conventional mixed-unit T/E2 number: testosterone in ng/dL divided by estradiol in pg/mL. It is not a dimensionless same-unit mass ratio. Input units are normalized before calculation using Mayo Clinic Laboratories conversion factors. A ratio does not establish a diagnosis, a hormonal balance target or a reason to start or adjust treatment. Timing, assay method and individual clinical circumstances affect interpretation. The result is an estimate for information only and is not medical advice.

Formula

Conventional T/E2 = testosterone ng/dL / estradiol pg/mL; same-unit mass ratio would be 10 times this number. Estradiol pg/mL × 3.671 = pmol/L. Testosterone ng/dL × 0.0347 = nmol/L.

Worked example

Testosterone 500 ng/dL and estradiol 100 pg/mL give the conventional mixed-unit number 5. The same values are 17.35 nmol/L and 367.1 pmol/L.

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Frequently asked questions

Does the ratio have a universal normal range?

No. This tool does not assign a diagnostic threshold or treatment target.

Why does unit convention matter?

Dividing unconverted laboratory numbers can change the ratio by a factor of ten or a thousand.

Can I use this to adjust hormones?

No. Treatment decisions require the complete clinical context and an appropriate clinician.

Sources

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